The study of metabolism addresses the vast genetic networks that contribute to complex diseases such as obesity. A National Institute of Health  Centers of Biomedical Research Excellence (COBRE) grant in mesenchymal and neural regulation of metabolic networks at Maine Medical Center Research Institute (MMCRI) is funding unique metabolic research into the signaling pathways generated by and impacting adipocytes, bone marrow, myoblasts, nervous tissue, and the cardiovascular system. Research is clarifying the role of aging and diseases such as type 2 diabetes on heart and nervous system health and investigating epigenetic contributions to gene regulation, the role of mitochondria in fat energy metabolism and the unique characteristics of brown fat. Study of the molecular regulators of variation is funded by a recent 9.6-million-dollar Transformative Research Award at Maine Medical Center Research Institute. 

Researchers in This Field