- Cornell University, 2004, B.S.
- University of Oregon, 2011, Ph.D.
- UC Berkeley, 2011-2012, Postdoc
- Ohio State University, 2012-2019, Postdoc
In order to produce conscious movement, our body contains hundreds of carefully positioned muscles, that are each endowed with specific contractile properties. The Talbot lab investigates how muscle precursor cells are positioned during embryonic development and how these precursors transform from motile cells into functional muscle fibers. To investigate muscle precursor development Dr Talbot uses zebrafish embryos, which have a comparatively simple musculature and can be imaged live at high resolution throughout their rapid embryonic development. Right now the Talbot lab is pursuing two projects: The first investigates how precursor cells migrate to the correct positions during development. The second project investigates how muscle cells generate contractile structures called sarcomeres. We are currently recruiting students to work on both projects.
Dr. Talbot received his Bachelors in Science in Biology from Cornell University. He then began his work on developmental biology by studying skeleton formation with Dr. Charles Kimmel at the University of Oregon. After this, he did a postdoc investigating muscle development with Sharon Amacher, initially working at the University of California Berkeley, then continuing the same work at The Ohio State University. Since becoming an assistant professor at the University of Maine in Orono, he has built a productive lab, received the Graduate Student Government’s Graduate Faculty Mentor Award, and the Chi-Bin Chien Award for new zebrafish investigators; he is also an investigator on the new COBRE grants and has secured R15 funding for the lab.
Below, you will see a select subset of our publications which provide a flavor of the lab’s work.
- Molecular and Cellular Biology
- Stem Cells
- DeLaurier AD*~, Howe DG, Ruzicka L, Carte AN, Hernandez LM, Wiggins KJ, Gallati MM, VanPelt K, Loyo Rosado F, Pugh KG, Shabdue CJ, Jihad K, Thyme SB, and Talbot JC*~. ZebraShare: A new venue for rapid dissemination of zebrafish mutant data. PeerJ, 2021 9:e11007.
- Chong J.X.*, Talbot J.C.* et al., Mutations in MYLPF Cause a Novel Segmental Amyoplasia that Manifests as Distal Arthrogryposis. American Journal of Human Genetics, 2020, 197(2) 293-310.
- Hromowyk K.J.*, Talbot J.C.*, Martin B.L, Janssen P.M.L., and Amacher S.L. Muscle fusion mechanisms in slow and fast muscle fibers differ between embryonic and juvenile zebrafish. Developmental Biology, 2020, 462(1), 85-100
- Talbot J.C., Teets E.M., Ratnayake D., Phan D.Q., Currie P.D., and Amacher S.L. Muscle precursor cell movements in zebrafish are dynamic and require Six family genes. Development, 2019, 146(10).
- Complete List of Published Work in My Bibliography: https://www.ncbi.nlm.nih.gov/myncbi/jared.talbot.1/bibliography/public/
Link to Laboratory Website: https://talbotlab.org