Molecular and Cellular Biology seeks mechanistic understanding of broad aspects of development and disease, including cell signal transduction, stem cell fate determination, and tissue homeostasis at multiple levels that include intermolecular, cell-cell, tissue and organ function. Related research within the GSBSE ranges from basic developmental and disease processes in cell and animal models from zebrafish to mouse, to studies in humans, which emphasize vascular biology, stem cell biology, tissue development, homeostasis and pathology. Learn more >
Neuroscience is an intrinsically broad discipline aimed at understanding large issues such as cognition, behavior, and neurological systems at levels that include the underlying anatomical and cellular circuits, and even the molecular events that control cell excitability, synaptic function, and development. Neuroscience research within the GSBSE ranges from psychology and psychometric studies in humans, to neuropharmacology and toxicology, to molecular genetics of neurodevelopment and neurodegenerative disease in model organisms. Learn more >
Biomedical Engineering may be defined as the application of engineering principles to promote and enhance the health and well-being of humans. Applications span the gamut of clinical, therapeutic and diagnostic arenas. Research strengths of the GSBSE include; artificial muscle, biomedical microdevices and microsystems, Lab-on-Chip, Biosensors, nanodevices and instruments, cell mechanics, robotic surgery, single molecule imaging, spectroscopy and microscopy of biological materials, and porous implants for tissue ingrowth. Learn more >
Toxicology is an applied discipline that incorporates and builds on a host of scientific disciplines to investigate the consequences of exposure to chemical agents on living organisms and the environment, and the cellular and molecular mechanisms that underlie those consequences. Research strengths of the GSBSE include; comparative marine toxicology, chemical carcinogenesis, immunotoxicology, toxicogenomics, neurotoxicology, and outer space toxicology. Learn more >
Research in bioinformatics and computational biology is an interdisciplinary area of study that brings together biologists, computer and information scientists, mathematicians, engineers, biophysicists, and chemists to examine fundamental biological processes through data intensive analysis and computational modeling.
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The Graduate School of Biomedical Science and Engineering (GSBSE) is a unique graduate program that includes the University of Maine as the degree granting institution and five additional cooperating academic and research institutions within Maine. The GSBSE offers a Ph.D. in Biomedical Science, a Ph.D. in Biomedical Engineering, and a Professional Science Masters (PSM) in BIoinformatics. Research Focus Areas of the program include Molecular and Cellular Biology, Bioinformatics & Genomics, Toxicology, Neuroscience, and Biomedical Engineering.
During their first year, Ph.D. students complete three core classes. Individual programs of study are then developed for each student with coursework relevant to his/her research topic. In addition to core coursework, during their first year in the program Ph.D. students undertake three laboratory research rotations hosted by faculty members in at least two of the six partner institutions. At the end of the rotation sequence students identify their dissertation mentor and project, and commence their thesis research.
With approximately 150 faculty members involved in the program, students have access to expertise in a broad range of research topics from world class leaders in these fields. The facilities available are all state-of-the-art, ranging from biomedical engineering fabrication and testing facilities, to cutting edge microscopy and spectroscopy centers, modern Zebrafish facilities, world class mouse facilities, animal imaging facilities, and genetic and bioinformatics resources.
Research findings are disseminated through national and international conferences, publication in high-profile scientific journals, and the patent literature. The GSBSE Ph.D. program is highly competitive, which makes available numerous research opportunities and provides a generous stipend. Interested applicants are encouraged to fill out an Advance Application form for further information.
The GSBSE also offers an online PSM program in Bioinformatics . The PSM degree is an interdisciplinary collaboration across the fields of mathematics, computer science, spatial information science and engineering, and molecular and cell biology. Students entering the program are expected to come from a cell and molecular biology background and require more intensive training in math, computer and information science, or from the mathematics, computer or information sciences disciplines and need training in cell and molecular biology. The program includes bioinformatics coursework, enrichment coursework, and six credits of applied field experience.