Romain Madelaine

Education

• Postdoctoral Fellow, Stanford University
• Ph.D., Toulouse University, 2011

Research Areas

• Neurobiology
• Developmental biology
• Aging

Brief Biography

Fishing for tissue regeneration: can the zebrafish reveal the key to unlocking regenerative potential in mammals?
Contrary to humans, some animals have the powerful capacity to fully regenerate damaged tissue and organs, including the nervous system. Dr. Madelaine’s research focuses on the function of the stem cell population during tissue regeneration, using the zebrafish as the model organism.

The Madelaine Lab takes advantage of cutting-edge techniques in functional genetic analysis by combining CRISPR-Cas-9 genome editing with Cre-Lox cell lineage tracing, single cell RNA-sequencing, and super-resolution confocal imaging to characterize the mechanisms of cellular regeneration. Their work aims to identify regenerative factors involved in stem cell activation and proliferation, to open new paths for tissue regeneration in humans.

Publications

Link to PubMed