Audrie Langlais

Education

• University of New England, 2018, B.S. Biochemistry

Brief Biography

My thesis research in the Motyl Lab focuses on understanding how the nervous system regulates bone mass within the context of Opioid use. In addition to addiction potential, opioids increase fracture risk and reduce bone mass but are often prescribed to treat musculoskeletal pain. Currently, I am investigating how miRNAs target genes that facilitate bone formation to cause bone loss. I first joined the Motyl Lab in 2018 as a Research Assistant after graduating with my Bachelor’s Degree and my interest in attending graduate school grew. In addition to research I enjoy mentoring undergraduate students and serving on the GSBSE Executive Committee. In my free time I enjoy spending time in Portland with friends, reading and cooking.

Publications

• Kunst R^, Langlais A^, Barlow D, Houseknecht KL, Motyl KJ. Housing temperature influences atypical antipsychotic drug-induced bone loss in C57BL/6J mice. JBMR-PLUS 2021. DOI: 10.1002/jbm4.10541. ^Co-first authorship 2.     Treyball A^, Bergeron AC^, Brooks DJ, Langlais AL, Hashmi H, Nagano K, Barlow D, Neilson RJ, Roy TA, Nevola KT, Houseknecht KL, Baron R, Bouxsein ML, Guntur AR, Motyl KJ. Propranolol promotes bone formation and limits resorption through novel mechanisms during anabolic parathyroid hormone treatment in female C57BL/6J mice. JBMR 2022. DOI:10.1002/jbmr.4523. ^Co-first authorship 3.     Carvalho AL, Brooks DJ, Barlow D, Langlais AL, Morrill B, Houseknecht KL, Bouxsein ML, Lian JB, King T, Farina NH, Motyl KJ. Sustained morphine delivery suppresses bone formation and alters metabolic and circulating miRNA profiles in male mice. JBMR 2022. DOI: 10.1002/jbmr.4690.