David Mokler


B.S. Psychology, Ph.D. Pharmacology/Toxicology and Neuroscience, Michigan State University


David Mokler, Ph.D. graduated from Michigan State University with a B.S. in Psychology and then went on to earn a Ph.D in Pharmacology/Toxicology and Neuroscience from Michigan State University with Richard Rech, Ph.D.  He then did a postdoctoral fellowship funded by the National Institute on Drug Abuse with John Rosecrans, Ph.D. at the Medical College of Virginia, Virginia Commonwealth University.  In 1986, he took a position as Assistant Professor at the University of New England College of Osteopathic Medicine. He rose to the rank of Professor in the Department of Pharmacology at the UNE College of Osteopathic Medicine.  He has served as department chair for the Department of Pharmacology in the College of Osteopathic Medicine.  He is currently Professor of Pharmacology in the Department of Biomedical Sciences in the UNE COM.  He is also a faculty member in the Center for Excellence in the Neurosciences.

Research Interests

David Mokler, Ph.D. is Professor of Pharmacology in the Department of Biomedical Sciences at the College of Osteopathic Medicine at the University of New England.  His research interests are in the area of the physiology and pharmacology of the forebrain.  His work has been funded by the National Institute of Drug Abuse, the National Institute of Child Health and Human Development and the National Institute of Mental Health.  His current work has focused on the development of the the prefrontal cortex of the rat with a focus on the effects of prenatal protein malnutrition.  Recent research has also focused on the organization of the serotonergic systems of the rat brain.  He has also worked on the effects of exposure to drugs of abuse on the brain.  He has lectured widely on topics in pharmacology and neuroscience and teaches pharmacology at the University of New England.

Selected Publications

  • Rech, R.H., Briggs, S.L. and Mokler, D.J. Fentanyl and spiradoline interactions in a place-conditioning black-white shuttle-box. Pharmaceuticals 4: 101-116, 2011. Download file (PDF)
  • Staiti, A.M., Morgane, P.J., Galler, J.R., Grivetti, J.Y., Bass, D.C., and Mokler, D.J. A microdialysis study of the medial prefrontal cortex of adolescent and adult rats. Neuropharmacology 61(3), 544-549, 2011. Download file (PDF)
  • Duncan, J.R., Paterson, D.S., Hoffman, J.M., Mokler, D.J., Borestein, N.S., Belliveau, R.A., Krous, H.F., Haas, E.A., Stanley, C., Nattie, E.E., Trachtenberg, F.L. and Kinney, H.C. Brainstem serotonergic deficiency in the sudden infant death syndrome. Journal of the American Medical Association, 303 (5): 430-437, 2010. Download file (PDF)
  • Mokler, D.J., Dugal, J.R., Hoffman, J.M. and Morgane, P.J. Functional interrelations between nucleus raphé dorsalis and nucleus raphé medianus: A dual probe microdialysis study of glutamate-stimulated serotonin release. Brain Research Bulletin, 78 (4-5): 132-138, 2009. Download file (PDF)
  • Mokler, D.J., Torres, O., Galler, J.R. and Morgane, P.J. Stress-induced changes in dopamine and serotonin in the medial prefrontal cortex and dorsal hippocampus of prenatally malnourished rats. Brain Res. 1148, 226-233, 2007. Download file (PDF)
  • Morgane, P.J. and Mokler, D.J. (eds.) Limbic Brain: Structure and Function. Special Issue, Neuroscience and Biobehavioral Reviews, 30(2), 2006.
  • Morgane, P.J. and Mokler, D.J. The limbic brain: Continuing Resolution. Neuroscience and Biobehavioral Reviews, 30(2), 119-125, 2006. Download file (PDF)
  • Morgane, P.J., Galler, J.R., Mokler, D.J. A review of systems and networks of the limbic forebrain/limbic midbrain. Prog. Neurobiol. 75(2): 143-160, 2005. Download file (PDF)
  • Turner,T.J., Mokler, D.J., Luebke, J.I. Calcium influx through presynaptic 5-HT3 receptors facilitates GABA release in the hippocampus: In vitro slice and synaptosome studies. Neuroscience 129 (3): 709-718, 2004. Download file (PDF)


  • 2007 to 2012 — $1,200,000.00 — Malnutrition and Mental Health from National Institute of Mental Health