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X-WR-CALNAME:Graduate School of Biomedical Science and Engineering
X-ORIGINAL-URL:https://gsbse.umaine.edu
X-WR-CALDESC:Events for Graduate School of Biomedical Science and Engineering
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DTSTART;TZID=America/New_York:20171002T130000
DTEND;TZID=America/New_York:20171002T140000
DTSTAMP:20260404T211007
CREATED:20170925T172521Z
LAST-MODIFIED:20230605T163848Z
UID:10000046-1506949200-1506952800@gsbse.umaine.edu
SUMMARY:Seminar - Reducing the Pain of Cardiac Electrical Therapies
DESCRIPTION:Abstract\nSince the discovery that electrical currents were important for cardiac function there has been\nintense interest in the development of cardiac electrical therapies. The most common cardiac\nelectrical therapies today are pacing and defibrillation\, which act to restore mechanical\nfunction and blood flow by correcting pathological electrical dysrhythmias. Each year over\n100\,000 implantable cardioverter defibrillators (ICDs) are implanted in the US alone\, and\ndespite significant research\, both ICDs and noninvasive pacing therapies are limited by the\ncommon issue of pain. The pain of electrical therapies is a well-studied yet poorly-understood\nlimitation that has created underserved clinical populations. My work to reduce pain uses\nbiophysically detailed computational models\, isolated muscle and heart preparations\, and\nlarge animal in vivo experiments. A novel method to quantify pain in animals was developed\nbased on extensive evidence suggesting that aberrant skeletal muscle contraction underlies\nshock-induced pain. This measurement\, the rate of force development (RoFD)\, was then\nused to develop a novel waveform to reduce pain caused by defibrillation. I will discuss this\nprior work\, other studies to reduce the pain of external cardiac pacing\, and ongoing work to\ntranslate our findings to human clinical application. \nSpeaker\nDr. Hunter is a 2010 graduate of the University of Maine’s Department of Electrical and Computer Engineering. After\ngraduation he pursued his doctorate in biomedical engineering at Johns Hopkins University where his research focused on\ncardiac electrophysiology\, specifically novel electrical therapies for cardiac arrhythmia. After he completed his Ph.D. he began\nresearch on atrial ablation therapies in the Johns Hopkins Medicine Cardiology department. He is also a lecturer in the\ndepartment of biomedical engineering and a consultant for a startup company that was founded on his Ph.D. research. \n 
URL:https://gsbse.umaine.edu/event/seminar-reducing-pain-cardiac-electrical-therapies/
LOCATION:Arthur St. John Hill Auditorium ESRB/Barrows Hall\, Orono\, ME\, 04468\, United States
CATEGORIES:Faculty,Student
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