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GSBSE

Molecular and Cellular Biology

Molecular and Cellular Biology seeks mechanistic understanding of broad aspects of development and disease, including cell signal transduction, stem cell fate determination, and tissue homeostasis at multiple levels that include intermolecular, cell-cell, tissue and organ function. Related research within the GSBSE ranges from basic developmental and disease processes in cell and animal models from zebrafish to mouse, to studies in humans, which emphasize vascular biology, stem cell biology, tissue development, homeostasis and pathology. Learn more >

Neuroscience

Neuroscience is an intrinsically broad discipline aimed at understanding large issues such as cognition, behavior, and neurological systems at levels that include the underlying anatomical and cellular circuits, and even the molecular events that control cell excitability, synaptic function, and development. Neuroscience research within the GSBSE ranges from psychology and psychometric studies in humans, to neuropharmacology and toxicology, to molecular genetics of neurodevelopment and neurodegenerative disease in model organisms. Learn more >

Biomedical Engineering

Biomedical Engineering may be defined as the application of engineering principles to promote and enhance the health and well-being of humans. Applications span the gamut of clinical, therapeutic and diagnostic arenas. Research strengths of the GSBSE include; artificial muscle, biomedical microdevices and microsystems, Lab-on-Chip, Biosensors, nanodevices and instruments, cell mechanics, robotic surgery, single molecule imaging, spectroscopy and microscopy of biological materials, and porous implants for tissue ingrowth. Learn more >

Toxicology

Toxicology is an applied discipline that incorporates and builds on a host of scientific disciplines to investigate the consequences of exposure to chemical agents on living organisms and the environment, and the cellular and molecular mechanisms that underlie those consequences. Research strengths of the GSBSE include; comparative marine toxicology, chemical carcinogenesis, immunotoxicology, toxicogenomics, neurotoxicology, and outer space toxicology. Learn more >

Bioinformatics and Computational Biology

Research in bioinformatics and computational biology is an interdisciplinary area of study that brings together biologists, computer and information scientists, mathematicians, engineers, biophysicists, and chemists to examine fundamental biological processes through data intensive analysis and computational modeling.
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Research Overview

The strength of the GSBSE program is the breadth of research that it encompasses. Students are encouraged to develop research projects involving studies in membrane biology, infectious disease and inflammation, muscle development, mathematical modeling, bioinformatics, cell signaling, cancer biology, toxicology, neurobiology and behavior.  Projects include in vitro and in vivo mouse models to study vascular development and the vascular response to injury, genetic and molecular basis of skeletal malformations, changes in the cellular composition of bone, stem cell biology, molecular mechanisms of red blood cell development, and cell signaling pathways that are disrupted during cancer progression and metastasis. GSBSE students conduct research that is vital to finding the causes and treatments for some of the world’s most intractable diseases and brings us closer to a complete understanding of the biological bases of cancer, diabetes, obesity, muscular dystrophy and many other genetic diseases and conditions.

 

State-of-the-art research facilities available to GSBSE students include cutting edge microscopy and spectroscopy centers, modern zebrafish facilities, world class mouse facilities, genetic and bioinformatics resources, and a wide range of research, fabrication and testing facilities, including a 3000 ft2 Class 1000 clean room, and advanced manufacturing center.

 


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Our Programs

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We offer 3 degree programs in five research focus areas. Learn more


UMaine The Jackson Laboratory Maine Medical Center Research Institute The Mount Desert Island Biological Laboratory University of Southern Maine University of New England
 
For more information about the program, please contact:
Tammy Crosby • 207-581-4654 • gsbse@maine.edu