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GSBSE

Molecular and Cellular Biology

Molecular and Cellular Biology seeks mechanistic understanding of broad aspects of development and disease, including cell signal transduction, stem cell fate determination, and tissue homeostasis at multiple levels that include intermolecular, cell-cell, tissue and organ function. Related research within the GSBSE ranges from basic developmental and disease processes in cell and animal models from zebrafish to mouse, to studies in humans, which emphasize vascular biology, stem cell biology, tissue development, homeostasis and pathology. Learn more >

Neuroscience

Neuroscience is an intrinsically broad discipline aimed at understanding large issues such as cognition, behavior, and neurological systems at levels that include the underlying anatomical and cellular circuits, and even the molecular events that control cell excitability, synaptic function, and development. Neuroscience research within the GSBSE ranges from psychology and psychometric studies in humans, to neuropharmacology and toxicology, to molecular genetics of neurodevelopment and neurodegenerative disease in model organisms. Learn more >

Biomedical Engineering

Biomedical Engineering may be defined as the application of engineering principles to promote and enhance the health and well-being of humans. Applications span the gamut of clinical, therapeutic and diagnostic arenas. Research strengths of the GSBSE include; artificial muscle, biomedical microdevices and microsystems, Lab-on-Chip, Biosensors, nanodevices and instruments, cell mechanics, robotic surgery, single molecule imaging, spectroscopy and microscopy of biological materials, and porous implants for tissue ingrowth. Learn more >

Toxicology

Toxicology is an applied discipline that incorporates and builds on a host of scientific disciplines to investigate the consequences of exposure to chemical agents on living organisms and the environment, and the cellular and molecular mechanisms that underlie those consequences. Research strengths of the GSBSE include; comparative marine toxicology, chemical carcinogenesis, immunotoxicology, toxicogenomics, neurotoxicology, and outer space toxicology. Learn more >

Bioinformatics and Computational Biology

Research in bioinformatics and computational biology is an interdisciplinary area of study that brings together biologists, computer and information scientists, mathematicians, engineers, biophysicists, and chemists to examine fundamental biological processes through data intensive analysis and computational modeling.
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Cancer

Researchers are identifying factors that initiate or predispose individuals to the cancer state and are uncovering ways to enhance the body’s ability to fight the uncontrolled growth of abnormal cells.

 
 

Faculty

Guangwen "Gary"  Ren

Guangwen "Gary" Ren

Interests: Tumor Microenvironment, Cancer Immunology, Cancer Therapeutic Resistance, Mesenchymal Stem Cells, Hematopoiesis

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Peter Brooks

Peter Brooks

Interests: Regulation of integrin-mediated cellular communication with the extracellular matrix (ECM) with angiogenesis, tumor growth and metastasis.

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Carol Bult

Carol Bult

Interests: bioinformatics, genomics, cancer, lung development and disease

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Robert Friesel

Robert Friesel

Interests: Growth factors (FGFs), signal transduction, vascular biology, skeletal development, cancer

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Joel Graber

Joel Graber

Interests: computational biology bioinformatics genomics mRNA processing gene expression polyadenylation post-transcriptional gene processing

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Olgun Guvench

Olgun Guvench

Interests: biomolecular simulation and computer-aided drug design; proteoglycans

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Joshua Kelley

Joshua Kelley

Interests: cell biology, biochemistry, yeast, actin, polarity, GPCR, Cdc42, gradient tracking, chemotropism, chemotaxis

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Andre Khalil

Andre Khalil

Interests: Image Analysis, Signal Processing, Computational Modeling

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Tamara King

Tamara King

Interests: chronic pain, neuropathic pain, osteoarthritis, cancer pain

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Lucy Liaw

Lucy Liaw

Interests: Vascular development and remodeling, cancer biology

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Mingyang Lu

Mingyang Lu

Interests: Cancer Systems Biology, Computaional Biology and Bioinformatics, Mathermatial Modeling, Gene Regulatory Network, Single Celll Genomics, Big Data

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Igor Prudovsky

Igor Prudovsky

Interests: Growth factors and cytokines in the cardiovascular system. Cell proliferation and senescence.

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Michaela Reagan

Michaela Reagan

Interests: blood cancer, multiple myeloma, bone microenvironment, 3D Models, in vivo models, oncology, marrow adipose, bone marrow niche, tumor-host interactions, biomedical engineering

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Sandra Rieger

Sandra Rieger

Interests: Regeneration, Peripheral nervous system, wound reapir

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Pradeep Sathyanarayana

Pradeep Sathyanarayana

Interests: Podocalyxin, microRNA, Acute Myeloid Leukemia, JAK2-STAT5 signaling

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Doug Spicer

Doug Spicer

Interests: Developmental biology and craniofacial development. Mesenchymal stem cell specification and differentiation.

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John Sundberg

John Sundberg

Interests: Mouse pathology, Diseases of the skin, hair, and nails, Junctional epidermolysis bullosa, alopecia areata, psoriasis, skin cancer, ichthiosis, pseudoxanthoma elasticum

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Cory Theberge

Cory Theberge

Interests: Lamin B nuclear receptor, cholesterol biosynthesis, veterinary pharmacology/pharmacy, organic/medicinal chemistry, drug stability, cholinergic pharmacology, LCMS

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Jennifer Trowbridge

Jennifer Trowbridge

Interests: cancer, hematopoiesis, stem cells, epigenetics

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Calvin Vary

Calvin Vary

Interests: Mechanisms of TGF-beta receptor regulation in vascular development and disease. Roles of endoglin in prostate cancer and its microenvironment. Study of biomedically-relevant models using mass spectrometry for quantitative protein analysis.

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Our Programs

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We offer 3 degree programs in five research focus areas. Learn more


UMaine The Jackson Laboratory Maine Medical Center Research Institute The Mount Desert Island Biological Laboratory University of Southern Maine University of New England
 
For more information about the program, please contact:
Tammy Crosby • 207-581-4654 • gsbse@maine.edu