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GSBSE

Molecular and Cellular Biology

Molecular and Cellular Biology seeks mechanistic understanding of broad aspects of development and disease, including cell signal transduction, stem cell fate determination, and tissue homeostasis at multiple levels that include intermolecular, cell-cell, tissue and organ function. Related research within the GSBSE ranges from basic developmental and disease processes in cell and animal models from zebrafish to mouse, to studies in humans, which emphasize vascular biology, stem cell biology, tissue development, homeostasis and pathology. Learn more >

Neuroscience

Neuroscience is an intrinsically broad discipline aimed at understanding large issues such as cognition, behavior, and neurological systems at levels that include the underlying anatomical and cellular circuits, and even the molecular events that control cell excitability, synaptic function, and development. Neuroscience research within the GSBSE ranges from psychology and psychometric studies in humans, to neuropharmacology and toxicology, to molecular genetics of neurodevelopment and neurodegenerative disease in model organisms. Learn more >

Biomedical Engineering

Biomedical Engineering may be defined as the application of engineering principles to promote and enhance the health and well-being of humans. Applications span the gamut of clinical, therapeutic and diagnostic arenas. Research strengths of the GSBSE include; artificial muscle, biomedical microdevices and microsystems, Lab-on-Chip, Biosensors, nanodevices and instruments, cell mechanics, robotic surgery, single molecule imaging, spectroscopy and microscopy of biological materials, and porous implants for tissue ingrowth. Learn more >

Toxicology

Toxicology is an applied discipline that incorporates and builds on a host of scientific disciplines to investigate the consequences of exposure to chemical agents on living organisms and the environment, and the cellular and molecular mechanisms that underlie those consequences. Research strengths of the GSBSE include; comparative marine toxicology, chemical carcinogenesis, immunotoxicology, toxicogenomics, neurotoxicology, and outer space toxicology. Learn more >

Bioinformatics and Computational Biology

Research in bioinformatics and computational biology is an interdisciplinary area of study that brings together biologists, computer and information scientists, mathematicians, engineers, biophysicists, and chemists to examine fundamental biological processes through data intensive analysis and computational modeling.
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Molecular and Cellular Biology

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GSBSE Student in Lab

Molecular and Cellular Biology seeks mechanistic understanding of broad aspects of development and disease, including cell signal transduction, stem cell fate determination, and tissue homeostasis at multiple levels that include intermolecular, cell-cell, tissue and organ function.  Molecular and Cellular Biology research within the GSBSE ranges from basic developmental and disease processes in cell and animal models from zebrafish to mouse, to studies in humans, which emphasize vascular biology, stem cell biology, tissue development, homeostasis and pathology. 

 
 

Faculty

Guangwen "Gary"  Ren

Guangwen "Gary" Ren

Interests: Tumor Microenvironment, Cancer Immunology, Cancer Therapeutic Resistance, Mesenchymal Stem Cells, Hematopoiesis

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Judith Blake

Judith Blake

Interests: Gene Ontology, Genome Informatics, Functional Genomics,

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Peter Brooks

Peter Brooks

Interests: Regulation of integrin-mediated cellular communication with the extracellular matrix (ECM) with angiogenesis, tumor growth and metastasis.

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Robert Burgess

Robert Burgess

Interests: Neurodevelopment, Synapse Formation

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Ling Cao

Ling Cao

Interests: Immunology, Neuroimmunology, Neuropathic pain

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James Coffman

James Coffman

Interests: Development, regeneration, aging, transcription, genomics, evolution

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Scott Collins

Scott Collins

Interests: MEMS, nanofabrication, micromechanical components, microphotonic devices

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Laurie Connell

Laurie Connell

Interests: Environmental Oceanography, Marine Physiological Ecology, Marine Molecular Genetics, Marine Biology

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Gregory Cox

Gregory Cox

Interests: Neuromuscular disease, mouse genetics, disease biology, motor neurons, skeletal muscles

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Robert Friesel

Robert Friesel

Interests: Growth factors (FGFs), signal transduction, vascular biology, skeletal development, cancer

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Joel Graber

Joel Graber

Interests: computational biology bioinformatics genomics mRNA processing gene expression polyadenylation post-transcriptional gene processing

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Thomas Gridley

Thomas Gridley

Interests: Birth defects, Developmental mutants, Notch signaling pathway in development and disease, Snail family genes, cardiovascular development

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Olgun Guvench

Olgun Guvench

Interests: biomolecular simulation and computer-aided drug design; proteoglycans

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Mary Ann Handel

Mary Ann Handel

Interests: Spermatogenesis, Testis Development, Infertility Genetic Models

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Clarissa Henry

Clarissa Henry

Interests: Cell and molecular biology of segmentation and muscle development in Zebrafish

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Sam Hess

Sam Hess

Interests: Super-Resolution Microscopy, Instrumentation Development, Biomembrane Organization, and Influenza

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Ronald Hills

Ronald Hills

Interests: multiscale modeling; multidrug resistance; lipid-protein interactions

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Karen Houseknecht

Karen Houseknecht

Interests: Pharmacology, endocrinology, toxicology, drug metabolism, drug discovery, diabetes, psychiatry

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Catherine Kaczorowski

Catherine Kaczorowski

Interests: learning, aging, plasticity, systems genetics, Alzheimer's disease, electrophysiology

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Andre Khalil

Andre Khalil

Interests: Image Analysis, Signal Processing, Computational Modeling

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Carol Kim

Carol Kim

Interests: Innate immunity, pathogens, bacteria, viruses, zebrafish, infection, TLR, cystic fibrosis, arsenic, immunology, toxicology, microbiology, super resolution microscopy

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Ron Korstanje

Ron Korstanje

Interests: Complex trait genetics, Systems genetics, Aging, Renal disease.

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Vivek Kumar

Vivek Kumar

Interests: addiction, functional genetics, neurobiology, reward pathways, cocaine, mouse genetics

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Lei Lei

Lei Lei

Interests: neuroscience, development, mouse genetics, gene expression, transcription factor, neural stem cell, sensory neuron, chronic pain, learning and memory, depression, seizure

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Lucy Liaw

Lucy Liaw

Interests: Vascular development and remodeling, cancer biology

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Vicki Losick

Vicki Losick

Interests: Wound healing, Regeneration, Aging, Drosophila

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Melissa Maginnis

Melissa Maginnis

Interests: virus, host-pathogen interactions, receptors, cell signaling, JC polyomavirus, PML

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Derek Molliver

Derek Molliver

Interests: Neuroscience, pain, GPCRs, plasticity, proteomics, signal transduction, protein translation

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Leif Oxburgh

Leif Oxburgh

Interests: embryonic kidney progenitor cells, organogenesis, tissue engineering, acute kidney injury

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Ilka Pinz

Ilka Pinz

Interests: Cardiovascular disease in obesity and hyperlipidemia

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Igor Prudovsky

Igor Prudovsky

Interests: Growth factors and cytokines in the cardiovascular system. Cell proliferation and senescence.

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Michaela Reagan

Michaela Reagan

Interests: blood cancer, multiple myeloma, bone microenvironment, 3D Models, in vivo models, oncology, marrow adipose, bone marrow niche, tumor-host interactions, biomedical engineering

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Sandra Rieger

Sandra Rieger

Interests: Regeneration, Peripheral nervous system, wound reapir

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Aric Rogers

Aric Rogers

Interests: Aging, lifespan, longevity, genetics, molecular biology, cellular homeostasis, stress response

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Derry Roopenian

Derry Roopenian

Interests: Immunobiology, autoimmune disease genetics, therapeutic antibodies

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Pradeep Sathyanarayana

Pradeep Sathyanarayana

Interests: Podocalyxin, microRNA, Acute Myeloid Leukemia, JAK2-STAT5 signaling

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Douglas Sawyer

Douglas Sawyer

Interests: cardiology, heart failure, cell signaling

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Doug Spicer

Doug Spicer

Interests: Developmental biology and craniofacial development. Mesenchymal stem cell specification and differentiation.

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John Sundberg

John Sundberg

Interests: Mouse pathology, Diseases of the skin, hair, and nails, Junctional epidermolysis bullosa, alopecia areata, psoriasis, skin cancer, ichthiosis, pseudoxanthoma elasticum

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Basile Tarchini

Basile Tarchini

Interests: Developmental biology, inner ear, cell polarity

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Kristy Townsend

Kristy Townsend

Interests: energy balance, brown adipose tissue, brown fat, brain, CNS, metabolism, neurobiology, neuroscience, obesity, neuropathy, energetics, diabetes, neurogenesis, appetite, sympathetic nerves, adipose tissue, neural plasticity, neurotrophic factors, fuel utilization

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Jennifer Trowbridge

Jennifer Trowbridge

Interests: cancer, hematopoiesis, stem cells, epigenetics

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Kerry Tucker

Kerry Tucker

Interests: primary cilia, Ift88, intraflagellar transport, midbrain, neurons, Shh, Kif3a, cerebral cortex, midbrain, spinal cord, dorsal root ganglia, DRG

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Dustin Updike

Dustin Updike

Interests: Regenerative Biology, Germline Development, Germ Granules, C. elegans

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Rebecca Van Beneden

Rebecca Van Beneden

Interests: Environmental Oceanography, Environmental Toxicology, Marine Molecular Genetics, Tumorigenesis, Molecular Carcinogenesis in Aquatic Organisms, Marine Biology

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Calvin Vary

Calvin Vary

Interests: Mechanisms of TGF-beta receptor regulation in vascular development and disease. Roles of endoglin in prostate cancer and its microenvironment. Study of biomedically-relevant models using mass spectrometry for quantitative protein analysis.

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Robert Wheeler

Robert Wheeler

Interests: Candida, innate immunity, host-pathogen, dendritic, functional genomics, anti-fungal, genetics, cell biology, molecular biology, microbiology

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Our Programs

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We offer 3 degree programs in five research focus areas. Learn more


UMaine The Jackson Laboratory Maine Medical Center Research Institute The Mount Desert Island Biological Laboratory University of Southern Maine University of New England
 
For more information about the program, please contact:
Tammy Crosby • 207-581-4654 • gsbse@maine.edu