The Molecular and Cellular Biology Track is an integrated, multidisciplinary graduate training program emphasizing gene function, animal development, and disease.
Molecular and Cellular Biology seeks mechanistic understanding of broad aspects of development and disease, including cell signal transduction, stem cell fate determination, and tissue homeostasis at multiple levels that include intermolecular, cell-cell, tissue and organ function.
Students in the Molecular and Cellular Biology Track will gain exposure to these fields through their course work, which will include classes in cell biology, developmental biology, biochemistry, and instrumentation, supplemented by the courses required of all Graduate School of Biomedical Sciences students.
These fields of study are reflected in the faculty participating in the Molecular and Cellular Biology Track. Research programs that are open for Ph.D. thesis work range from basic developmental and disease processes in cell and animal models from zebrafish to mouse, to studies in humans, which emphasize vascular biology, stem cell biology, tissue development, homeostasis and pathology. The focus of students' theses will largely be determined by the choice of thesis laboratory, but it is anticipated that the integrated nature of the field will be reflected in the course work and thesis committee members, which are likely to be from multiple participating institutions.
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Interests:
Gene Ontology, Genome Informatics, Functional Genomics,
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Interests:
Regulation of integrin-mediated cellular communication with the extracellular matrix (ECM) with angiogenesis, tumor growth and metastasis.
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Immunology, Neuroimmunology, Neuropathic pain
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Interests:
Development, embryo, transcription, genomics, evolution
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Interests:
MEMS, nanofabrication, micromechanical components, microphotonic devices
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Interests:
Neuromuscular disease, mouse genetics, disease biology, motor neurons, skeletal muscles
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Interests:
epilepsy, genetics, complex traits, neurogenetics
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Interests:
Growth factors (FGFs), signal transduction, vascular biology, skeletal development, cancer
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Interests:
computational biology bioinformatics genomics mRNA processing gene expression polyadenylation post-transcriptional gene processing
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Interests:
Birth defects, Developmental mutants, Notch signaling pathway in development and disease, Snail family genes, cardiovascular development
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Interests:
biomolecular simulation and computer-aided drug design; role of the microenvironment in cancer
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Interests:
Spermatogenesis, Testis Development, Infertility Genetic Models
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Interests:
Cell and molecular biology of segmentation and muscle development in Zebrafish
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Interests:
Super-Resolution Microscopy, Instrumentation Development, Biomembrane Organization, and Influenza
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Interests:
multiscale modeling; multidrug resistance; lipid-protein interactions
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Interests:
DNA replication and repair; mutagenesis; oncology and drug target identification
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Interests:
Image Analysis, Signal Processing, Computational Modeling
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Interests:
Zebrafish, zebrafish disease, disease modeling, infection
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Interests:
Complex trait genetics,
Systems genetics,
Cardiovascular disease,
Renal disease.
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Interests:
Cell signaling Molecular Biology Fibrotic Remodeling
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Interests:
Vascular development and remodeling, cancer biology
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Interests:
DNA Repair, Immune system development, Genome stability, and Cancer
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Interests:
embryonic kidney progenitor cells, organogenesis, tissue engineering, acute kidney injury
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Interests:
Lymphocyte Regulation and the Development of Autoimmunity
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Interests:
Cardiovascular disease in obesity and hyperlipidemia
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Interests:
Growth factors and cytokines in the cardiovascular system. Cell proliferation and senescence.
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Interests:
Regeneration, Peripheral nervous system, wound reapir
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Interests:
Immunobiology, autoimmune disease genetics, therapeutic antibodies
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Interests:
Podocalyxin, microRNA, Acute Myeloid Leukemia, JAK2-STAT5 signaling
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Interests:
Muscular Dystrophy, mitochondrial dynamics, Amyotrophic lateral sclerosis, Neurodegeneration, nucleo-cytoplasmic transport
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Interests:
Genome Structure and Function Within the Nucleus
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Interests:
Developmental biology and craniofacial development. Mesenchymal stem cell specification and differentiation.
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Interests:
signal transduction, molecular biology, cell biology, drug discovery, receptors, Opioids, pain
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Interests:
cancer, hematopoiesis, stem cells, epigenetics
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Interests:
Regenerative Biology, Germline Development, Germ Granules, C. elegans
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Interests:
Environmental Oceanography, Environmental Toxicology, Marine Molecular Genetics, Tumorigenesis, Molecular Carcinogenesis in Aquatic Organisms, Marine Biology
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Interests:
Mechanisms of TGF-beta receptor regulation in vascular development and disease. Roles of endoglin in prostate cancer and its microenvironment. Study of biomedically-relevant models using mass spectrometry for quantitative protein analysis.
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Interests:
Numb/ Notch signaling/ Neural Development/ Apoptosis / MS
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Interests:
Candida, innate immunity, host-pathogen, dendritic, functional genomics, anti-fungal, genetics, cell biology, molecular biology, microbiology
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Interests:
Metals, chromium, chromate, particulates, marine mammals, whales, toxicology, carcinogenesis, genetic toxicology, mitosis, chromosome, metaphase, arsenic, depleter uranium, lunar dust, DNA repair, cancer
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Interests:
Marine Conservation and Environmental Science
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Interests:
Wnt signaling in mouse development and tissue regeneration
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