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GSBSE

Molecular and Cellular Biology

The Molecular and Cellular Biology Track is an integrated, multidisciplinary graduate training program emphasizing gene function, animal development, and disease. Learn more >

Neuroscience

The Neuroscience Track is an integrated, interdisciplinary graduate training program examining the functions of the nervous system. Learn more >

Biomedical Engineering

Students in the Biomedical Engineering track receive training in the biological, physical and computational sciences through a combination of core and advanced courses, and interdisciplinary research. Learn more >

Toxicology

The Toxicology Track is an innovative, multidisciplinary graduate program investigating the consequences of exposure to chemical agents on living organisms and the environment. Learn more >

Functional Genomics

The Functional Genomics Track is a highly interactive, interdisciplinary program that brings together biologists, computer and information scientists, mathematicians, engineers, biophysicists, and chemists to examine fundamental biological processes related to gene and protein function and interactions. Learn more >

 

Functional Genomics

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The major challenge in biomedical and biological research for now and the foreseeable future is to understand how the information encoded by the genome determines an organism's functions. To move from the level of the DNA sequence to an understanding of the morphogenetic and physiological pathways crucial for normal development requires new approaches to acquiring and analyzing data on a genome-wide scale.  The field of Functional Genomics is a highly interactive, interdisciplinary research environment that brings together biologists, computer and information scientists, mathematicians, engineers, biophysicists, and chemists to examines fundamental biological processes and improves our understanding of  related to gene and protein function and interactions. Dynamic aspects of gene transcription, translation, and protein-protein interactions are analyzed. Under the guidance of two mentors, one in the biological sciences and one in the computational/ or physical sciences, students in the Functional Genomics Track program merge these fields to develop a multidisciplinary, multidimensional program of study. The degree program provides a bridge that links a set of interdependent research cores in genetics/genomics, cell/molecular biology, biophysics/bioengineering, and computational biology/bioinformatics. Examples of ongoing research projects include super-resolution imaging of viral entry into cells, mathematical modeling of muscle development, and spectroscopic analysis of non-canonical protein translocation.

 
 

Faculty

Susan Ackerman

Susan Ackerman

Interests: Neurodegeneration, Neurodevelopment

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Judith Blake

Judith Blake

Interests: Gene Ontology, Genome Informatics, Functional Genomics,

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Peter Brooks

Peter Brooks

Interests: Regulation of integrin-mediated cellular communication with the extracellular matrix (ECM) with angiogenesis, tumor growth and metastasis.

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Carol Bult

Carol Bult

Interests: bioinformatics, genomics, cancer, lung development and disease

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Robert Burgess

Robert Burgess

Interests: Neurodevelopment, Synapse Formation

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Gary Churchill

Gary Churchill

Interests: Statistical Genetics, QTL Analysis

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James Coffman

James Coffman

Interests: Development, regeneration, aging, transcription, genomics, evolution

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Scott Collins

Scott Collins

Interests: MEMS, nanofabrication, micromechanical components, microphotonic devices

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Gregory Cox

Gregory Cox

Interests: Neuromuscular disease, mouse genetics, disease biology, motor neurons, skeletal muscles

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Wayne Frankel

Wayne Frankel

Interests: epilepsy, genetics, complex traits, neurogenetics

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Joel Graber

Joel Graber

Interests: computational biology bioinformatics genomics mRNA processing gene expression polyadenylation post-transcriptional gene processing

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Mary Ann Handel

Mary Ann Handel

Interests: Spermatogenesis, Testis Development, Infertility Genetic Models

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Clarissa Henry

Clarissa Henry

Interests: Cell and molecular biology of segmentation and muscle development in Zebrafish

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Sam Hess

Sam Hess

Interests: Super-Resolution Microscopy, Instrumentation Development, Biomembrane Organization, and Influenza

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Matthew Hibbs

Matthew Hibbs

Interests: computational biology, bioinformatics, machine learning, data mining, visualization

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Keith Hutchison

Keith Hutchison

Interests: functional genomics, gene expression, nuclear organization, transposons

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Andre Khalil

Andre Khalil

Interests: Image Analysis, Signal Processing, Computational Modeling

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Carol Kim

Carol Kim

Interests: Innate immunity, pathogens, bacteria, viruses, zebrafish, infection, TLR, cystic fibrosis, arsenic, immunology, toxicology, microbiology, super resolution microscopy

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Ron Korstanje

Ron Korstanje

Interests: Complex trait genetics, Systems genetics, Cardiovascular disease, Renal disease.

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Lei Lei

Lei Lei

Interests: neuroscience, development, mouse genetics, gene expression, transcription factor, neural stem cell, sensory neuron, chronic pain, learning and memory, depression, seizure

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Lucy Liaw

Lucy Liaw

Interests: Vascular development and remodeling, cancer biology

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Paul Millard

Paul Millard

Interests: biosensors, microbial pathogen detection

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David Neivandt

David Neivandt

Interests: Determination of the orientation and conformation of interfacial species; surface spectroscopies/microscopies; model cellular membranes; biological and chemical sensors

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Leif Oxburgh

Leif Oxburgh

Interests: embryonic kidney progenitor cells, organogenesis, tissue engineering, acute kidney injury

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Sandra Rieger

Sandra Rieger

Interests: Regeneration, Peripheral nervous system, wound reapir

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Lindsay Shopland

Lindsay Shopland

Interests: Genome Structure and Function Within the Nucleus

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Rosemary Smith

Rosemary Smith

Interests: Microfluidic instruments for biomolecular analysis, microsensors, biomedical microdevices

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Cory Theberge

Cory Theberge

Interests: Lamin B nuclear receptor, cholesterol biosynthesis, veterinary pharmacology/pharmacy, organic/medicinal chemistry, drug stability, cholinergic pharmacology, LCMS

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Robert Wheeler

Robert Wheeler

Interests: Candida, innate immunity, host-pathogen, dendritic, functional genomics, anti-fungal, genetics, cell biology, molecular biology, microbiology

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Kyuson Yun

Kyuson Yun

Interests: stem cells cancer development brain

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Our Programs

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Our programs include 5 tracks and more than 10 research areas.
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UMaine The Jackson Laboratory Maine Medical Center Research Institute The Mount Desert Island Biological Laboratory University of Southern Maine University of New England
 
For more information about the program, please contact:
Laura Hall, GSBSE Administrative Assistant • 207-581-4654 • gsbse@maine.edu