Skip to main content

GSBSE

Molecular and Cellular Biology

The Molecular and Cellular Biology Track is an integrated, multidisciplinary graduate training program emphasizing gene function, animal development, and disease. Learn more >

Neuroscience

The Neuroscience Track is an integrated, interdisciplinary graduate training program examining the functions of the nervous system. Learn more >

Biomedical Engineering

Students in the Biomedical Engineering track receive training in the biological, physical and computational sciences through a combination of core and advanced courses, and interdisciplinary research. Learn more >

Toxicology

The Toxicology Track is an innovative, multidisciplinary graduate program investigating the consequences of exposure to chemical agents on living organisms and the environment. Learn more >

Functional Genomics

The Functional Genomics Track is a highly interactive, interdisciplinary program that brings together biologists, computer and information scientists, mathematicians, engineers, biophysicists, and chemists to examine fundamental biological processes related to gene and protein function and interactions. Learn more >

 

Marie J. Hayes

Marie J. Hayes

Contact Information

Phone:
(207) 973-4963

Email/web:
mhayes@maine.edu
View Website
Download CV

Address:
Psychology Dept.
University of Maine & Maine Institute for Human Genetics & Health 
Orono, ME  04469

Education

Ph.D. in Experimental Psychology, Postdoctoral in Neuropharmacology

Research Interests

 Our laboratory uses neurophysiological behavioral and actigraphic recordings for sleep studies to examine CNS functioning in high risk human neonate. Based on animal model findings demonstrating disruption of cholinergic neurotransmission with prenatal exposure to opioid compounds such as methadone, we have been testing early electrophysiological correlates of prefrontal development of attention and recognition memory in neonates in withdrawal from prenatal opioid exposure.  Our previous work in normative and high risk samples has investigated the hypothesis that the pattern and rhythmicity of sleep-dependent spontaneous movements functions as a primitive arousal system that is protective for Sudden Infant Death Syndrome. High risk for SIDS samples such as premature infants with apnea and dysmature infants, e.g. prenatally exposed to opiates, alcohol, tobacco, are found to have reductions in the robustness of this system.  

Another line of work examines prospectively the development of anxiety disorders in children following trauma and under laboratory conditions of mild stress. Future studies will incorporate neuroendocrine/neurobiological correlates of stress reactivity such as NPY, CRH and cortisol during the development of the stress disorder. 

Selected Publications

In Press

  • Hayes, M.J., McCoy, S.K., DiPietro, J.A., Fukumizu, M. & Joseph D. Wellman. (in press). Temperament and sleep-wake behaviors from infancy to toddlerhood. Infant and Child Development.

Additional Publications

  • Matano, B.A., Hayes, M.J., Brown, M., Tisher, P., Krishnan R. and Paul, J.A. (2009). Main’s high risk infants and maternal helath and wellbeing, Maine Policy Review, 18, 60-65.
  • Troese, M., Sallinen, B.J., Gilles, A.A., Troese, M., Fukumizu, M., Brown, E. & Hayes, M.J. (2008). Sleep fragmentation and evidence for sleep debt in alcohol-exposed infants. Early Human Development, 80, 577-585.
  • Giganti, F., Hayes, M.J., Cioni, G. & Salzarulo, P. (2007) Yawning frequency and distribution in preterm and nearterm infants assessed through 24 hour recordings. Infant Behavior & Development, 30, 641-647.
  • Hayes, M.J., Fukumizu, M., Troese, M., Sallinen, B.J. & Gilles, A.A. (2007). Social experiences in infancy and early childhood co-sleeping. Infant & Child Development, 16, 403-416.
  • Hayes, M. J., Akilesh, M. R., Gilles, A. A., Fukumizu, M., Sallinen, B.J., & Troese, M. (2007). Apneic preterms and methylxanthines: Arousal deficits, sleep fragmentation and suppressed spontaneous movement. Journal of Perinatology, 27, 782–789.
  • Fukumizu, M., Kaga, M., Kohyama, J. & Hayes, M.J. (2005). Sleep-related night-time crying (“yonaki”) in Japan: A community study, Pediatrics. 115, 217-224
  • Symanski, M.E., Hayes, M.J., & Akilesh, M.K. (2002). Patterns of premature newborns’ sleep-wake states before and after nursing interventions on the night shift. JOGNN, 31, 305-313.
  • Hayes, M. J., Brown, E., Hofmaster, P., Davare, A., Parker, K. G., & Raczek, J. A. (2002). Prenatal alcohol intake in a rural, Caucasian clinic. Family Medicine, 34(2), 120-125.
  • Giganti, F., Hayes, M. J., Akilesh, M. R., & Salzarulo, P. (2002). Yawning and behavioral status in preterm infants. Developmental Psychobiology, 41, 289-296.
  • Hayes, M. J., Parker, K. G., Sallinen, B., & Davare, A. (2001). Bedsharing, temperament and sleep disturbance in early childhood. Sleep, 24, 657-662
  • Hayes, M. J., Roberts, S., & Davare, A. A. (2000). Transactional conflict between psychobiology and culture in the etiology of postpartum depression. Medical Hypothesis, 54, 7-17.
  • Hayes, M. J., & Mitchell, D. (1998). Spontaneous movements during sleep: Temporal organization and changes with age. Developmental Psychobiology, 32, 13-21.

Service

Community Service

  • 2009 — Scientific Advisory Board, Sarah Jane Brain Foundation
  • 2010 — Maine Chapter for the Society for Neuroscience

University Service

  • 2007 to 2008 — UMS Trustee Professor
  • 2007 — Lead Coordinator, Maine Neurogenetics Consortium
  • 2010 — Outstanding Research & Creative Achievement, Liberal Arts & Sciences

Find a mentor

Find a GSBSE mentor icon

Search by keyword to find a faculty mentor in your area of interest.
Find a mentor at GSBSE

Our Programs

Info icon

Our programs include 5 tracks and more than 10 research areas.
Learn more

Apply Now

Apply to GSBSE

Become a GSBSE student -- Start your advance application online

UMaine The Jackson Laboratory Maine Medical Center Research Institute The Mount Desert Island Biological Laboratory University of Southern Maine University of New England
 
For more information about the program, please contact:
Laura Hall, GSBSE Administrative Assistant • 207-581-4654 • gsbs@maine.edu