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GSBSE

Molecular and Cellular Biology

The Molecular and Cellular Biology Track is an integrated, multidisciplinary graduate training program emphasizing gene function, animal development, and disease. Learn more >

Neuroscience

The Neuroscience Track is an integrated, interdisciplinary graduate training program examining the functions of the nervous system. Learn more >

Biomedical Engineering

Students in the Biomedical Engineering track receive training in the biological, physical and computational sciences through a combination of core and advanced courses, and interdisciplinary research. Learn more >

Toxicology

The Toxicology Track is an innovative, multidisciplinary graduate program investigating the consequences of exposure to chemical agents on living organisms and the environment. Learn more >

Functional Genomics

The Functional Genomics Track is a highly interactive, interdisciplinary program that brings together biologists, computer and information scientists, mathematicians, engineers, biophysicists, and chemists to examine fundamental biological processes related to gene and protein function and interactions. Learn more >

 

Amanda Favreau

Amanda Favreau

Contact Information

Phone:
(207) 396-8207

Email/web:
favrea2@mmc.org
View Website


Education

Post-Baccalaureate Fellowship, Rocky Mountain Laboratories, NIAID, NIH 2008-2010, B.S. Biochemistry, Chestnut Hill College, Philadelphia, PA 2008

Biosketch

I am a first year GSBS student in the Molecular and Cellular Biology track currently in the rotation phase of the program.  My research background began during undergraduate school when I was part of the 2007 Summer Student Research Program in Dr. Calvin Vary's laboratory at Maine Medical Center Research Institute.  After obtaining a B.S. in Biochemistry in 2008, I moved to Hamilton, Montana to work for Dr. Steve Porcella at Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH).  During my time in Dr. Porcella's laboratory I was a recipient for a 1-year Post-Baccalaureate Intramural Research Training Award Fellowship, which was extended for a second year.  Dr. Porcella's laboratory provides state-of-the-art research technologies for NIAID's intramural infectious diseases, allergy, and immunology research programs within the Division of Intramural Research, NIAID, NIH.  My time working for Dr. Porcella enhanced my career in many ways by allowing me to learn multiple high-end technologies while working with leading scientists within the fields of allergies and infectious diseases.  My time can most notably be shown in the six peer-reviewed manuscripts I contributed to, as well as, a National Institutes of Health Director's Award that was awarded for being part of the group who identified the genetic cause of a previously undefined primary immune deficiency disease (see NEJM manuscript).  After completing my two-year fellowship award, I moved back to Maine in July 2010 and began working in Dr. Pradeep Sathyanarayana’s laboratory at Maine Medical Center Research Institute as a Research Technologist where studies have been focused on the functional and prognostic roles of microRNA in acute myeloid leukemia.  My first rotation was in Dr. Sathyanarayana's laboratory as a continuation of my time there as a research technologist.  My second rotation was in Dr. Vary's laboratory at Maine Medical Center Research Institute looking at the functional role BMP9 can have on endothelial cells in relation to the various extracellular matrix components, and the relevance to vascular disease, including hereditary hemorrhagic telangiectasia (HHT).  My final rotation was in Dr. Olgun Guvench's laboratory at University of New England School of Pharmacy learning biomolecular simulation software systems and utilizing these systems to observe interactions between CD44 and hyaluronan.  As of July 2012 I have returned to Dr. Sathyanarayana's laboratory for my thesis research.

Selected Publications

  • Favreau A.J., Cross E., Sathyanarayana, P. 2012. miR-199b-5p directly targets PODXL and DDR1 and decreased levels of miR-199b-5p correlate with elevated expressions of PODXL and DDR1 in Acute Myeloid Leukemia. American Journal of Hematology. 28 FEB 2012 | DOI: 10.1002/ajh.23129 Read Abstract
  • Dostalova, A., Votypka, J., Favreau, A.J., Barbian, K.D., Volf, P., Valenzuela, J.G., and Jochim, R.C. 2011. The midgut transcriptome of Phlebotomus (Larroussius) perniciosus, a vector of Leishmania infantum: comparison of sugar fed and blood fed sand flies. BMC Genomics 12:223. Read Abstract
  • Favreau AJ, Sathyanarayana P. miR-590-5p, miR-219-5p, miR-15b and miR-628-5p are commonly regulated by IL-3, GM-CSF and G-CSF in acute myeloid leukemia. Leuk Res (2011), doi:10.1016/j.leukres.2011.09.027 Read Abstract
  • Ribeiro, J.M., Valenzuela, J.G., Pham, V.M., Kleeman, L., Barbian, K.D., Favreau, A.J., Eaton, D.P., Aoki, V., Hans-Filho, G., Rivitti, E.A., et al. 2010. An insight into the sialotranscriptome of Simulium nigrimanum, a black fly associated with fogo selvagem in South America. Am J Trop Med Hyg 82:1060-1075. Read Abstract
  • Calvo, E., Sanchez-Vargas, I., Kotsyfakis, M., Favreau, A.J., Barbian, K.D., Pham, V.M., Olson, K.E., and Ribeiro, J.M. 2010. The salivary gland transcriptome of the eastern tree hole mosquito, Ochlerotatus triseriatus. J Med Entomol 47:376-386. Read Abstract
  • Francischetti, I.M., Calvo, E., Andersen, J.F., Pham, V.M., Favreau, A.J., Barbian, K.D., Romero, A., Valenzuela, J.G., and Ribeiro, J.M. 2010. Insight into the Sialome of the Bed Bug, Cimex lectularius. J Proteome Res 9:3820-3831. Read Abstract
  • Calvo, E., Sanchez-Vargas, I., Favreau, A.J., Barbian, K.D., Pham, V.M., Olson, K.E., and Ribeiro, J.M. 2010. An insight into the sialotranscriptome of the West Nile mosquito vector, Culex tarsalis. BMC Genomics 11:51. Read Abstract
  • Zhang, Q., Davis, J.C., Lamborn, I.T., Freeman, A.F., Jing, H., Favreau, A.J., Matthews, H.F., Davis, J., Turner, M.L., Uzel, G., et al. 2009. Combined immunodeficiency associated with DOCK8 mutations. N Engl J Med 361:2046-2055. Read Abstract


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Our programs include 5 tracks and more than 10 research areas.
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UMaine The Jackson Laboratory Maine Medical Center Research Institute The Mount Desert Island Biological Laboratory University of Southern Maine University of New England
 
For more information about the program, please contact:
Laura Hall, GSBSE Administrative Assistant • 207-581-4654 • gsbs@maine.edu